Título del estudio: Dermal Irritability 3 Day Dosing Study of Ion Gel ZCM-25® on New Zealand Male Rabbits.
Autor: Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco A.C, - CIATEJ. Dr. en C. Eduardo Padilla Camberos (2018).
Métodos: A dermal irritation study of the product Ion Gel ZCM-25® as a daily dose of 0.5 ml over 6 cm x 6 cm (32.0 sq cm) administered each day for 3 days on the skin of New Zealand male rabbits. The dose used was 5 times higher than human dosing as described in the current user manual for humans use.
Resultados: No es irritante, valores de irritación de la piel <1.5.
Conclusiones: In the present study, the sample of the product Ion Gel ZCM-25® is considered a Non-irritant according to the GHS system. The average values of dermal irritation were lower than 1.5 for all 3 test animals.