Resources & Studies

Ion Gel ZCM-25® Officially Registered as a Class II Medical Device in the UAE

In 2025, Ion Gel ZCM-25®, a Class II medical device produced in Mexico by…
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May 2, 2025

Ion Gel ZCM-25® in the Treatment of Lyme Disease Targeting Borrelia burgdorferi

Background Lyme disease, caused by the spirochete bacterium Borrelia burgdorferi, transmitted through Ixodes tick…
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July 10, 2024

Efficacy of Ion Gel ZCM-25® in the Antiviral Treatment Against Dengue Virus

Background Dengue virus is a significant pathogen responsible for various infections, especially in healthcare…
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June 18, 2024

Efficacy of Ion Gel ZCM-25® in the Antimicrobial Treatment Against Acinetobacter baumannii

Background Acinetobacter baumannii is a pathogenic bacterium responsible for a range of infections, particularly…
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March 24, 2024

Assessment of the Antifungal Efficacy of Ion Gel ZCM-25® Against Candida auris

Background Candida auris is an emerging fungal pathogen known for its resistance to conventional…
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March 23, 2024

Modification to the Conditions of the Sanitary Registration due to Change of Nacional Manufacturer

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At the beginning of 2023, a request was made to the Federal Commission for…
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March 22, 2024

Preclinical Study PK & Oxidative Stress Reduction

In a preclinical study completed in November 2023, led by Dr. José Trinidad Pérez…
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November 18, 2023

Phase I study to determine the topical tolerability of Ion Gel ZCM-25®.

This study aimed to evaluate the tolerability of Ion Gel ZCM-25® as a topical…
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April 27, 2023

Cofepris Approval of the Ion Gel ZCM-25®

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The Mexican Health Department Cofepris approved the Ion Gel ZCM-25® as a Medical Device…
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February 2, 2021

Ion Gel ZCM-25® Phase 1 Clinical Study on Humans

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In the present study, the tolerability of the Class II Medical Device, Ion Gel…
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October 5, 2020

ION GEL ZCM-25® User Manual

ION GEL ZCM-25® User Manual in Spanish and English
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September 21, 2020

Anti-MRSA disinfectant Activity By a Bacterial Challenge MRSA

Abstract     Author Laboratory of Immunological Specialties. LEI. M. en C. Israel Velázquez…
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August 5, 2020

Antifungal Disinfectant Activity by Fungicide Challenge - Aspergillus Brasiliensis

Abstract   Author Laboratories of Immunological Specialties. LEI. M. en C. Israel Velázquez Martínez.…
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August 3, 2020

Ion Gel ZCM-25® Dosing Comparison Chart

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Ion Gel ZCM-25® dosing comparison chart across several human and animal dosing studies.
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July 24, 2020

Research Manual for Ion Gel ZCM-25®

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The Ion Gel ZCM-25® has a unique aqueous ligand transport system (Hexa-Aqua), which provides…
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July 20, 2020

Antiviral Activity of Ion Gel ZCM-25® on SARS-CoV-2 Equine Viral Arteritis

Abstract   Study Title Antiviral Activity of Ion Gel ZCM-25® on SARS-CoV-2 Author Laboratory…
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June 7, 2020

ANTIMICROBIAL - Bacterial & Fungal Challenge Test 2 - Six Month Stability 3 Lots of Ion Gel ZCM-25®

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Abstract   Study Title ANTIMICROBIAL - Bacterial & Fungal Challenge Test 2 - Six…
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April 2, 2020

ANTIMICROBIAL - Gram Negative - Gram Positive Bacterial Challenge Test of ION-ZCM1

Abstract   Author Laboratorio de Control - ARJ - Principle Investigator QFB Rocio Guadalupe…
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December 9, 2019

ANTIMICROBIAL - Gram Negative - Gram Positive Bacterial Challenge Test of Ion Gel ZCM-25®

Abstract   Study Title ANTIMICROBIAL - Gram Negative - Gram Positive Bacterial Challenge Test…
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December 9, 2019

ANTIMICROBIAL - Bacterial & Fungal Challenge Test 1 4 Lots of Ion Gel ZCM-25®

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Abstract   Study Title ANTIMICROBIAL - Bacterial & Fungal Challenge Test 1 - 4…
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August 30, 2019

Dermal Irritability Single High Dose Study of Ion Gel ZCM-25® on New Zealand Male Rabbits

Abstract   Study Title Dermal Irritability Single High Dose Study of Ion Gel ZCM-25®…
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August 13, 2019

ION-ZCM1 is Classified as a Small Molecule

The Ion Gel ZCM-25® has a unique aqueous ligand transport system (Hexa-Aqua), which gives…
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March 14, 2019

Oxygen Radical Absorbance Capacity - ORAC Activity of ION-ZCM1

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Abstract   Study Title Oxygen Radical Absorbance Capacity - ORAC Activity of ION-ZCM1 Author…
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August 16, 2018

Dermal Irritability 3 Day Dosing Study of Ion Gel ZCM-25® on New Zealand Male Rabbits.

Abstract   Study Title Dermal Irritability 3 Day Dosing Study of Ion Gel ZCM-25®…
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July 19, 2018

In vitro Toxicity Study of ION-ZCM1 on Human Cells Using an MTT Cytotoxicity Test Method

Abstract   Study Title In vitro Toxicity Study of ION-ZCM1 on Human Cells Using…
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June 26, 2018

ION-ZC1 Antimicrobial Study 3 - MRSA in Biofilm

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Abstract   Study Title ION-ZC1 Antimicrobial Study 3 - MRSA in Biofilm Author INDEVION…
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March 7, 2018

ION-ZC1 Antimicrobial Study 2 MRSA Non-biofilm Comparing Vancomycin as a Control

Abstract   Study Title ION-ZC1 Antimicrobial Study 2 MRSA Non-biofilm Comparing Vancomycin as a…
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March 1, 2018

ION-ZC1 Antimicrobial Study 1 - Bacterial - Fungal - 12 Hospital Acquired Pathogens

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Abstract   Author Dr. Zsolt Keresztessy INDEVION Biotechnology Research and Development Ltd. (2018). Methods…
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July 19, 2017
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